Research progress of organoids derived from normal tissues

Huan Li, Shuhao Liu, Junchang Zhang, Changhua Zhang

Abstract

Organoids are self-organizing three-dimensional tissue structures formed from stem cells extracted from healthy or diseased individuals in vitro. Organoid technology plays an important role in disease modeling, tissue development research, drug testing and regenerative medicine. This article reviews the development history, culture methods, classification, application, discussion, conclusions and prospects of organoids derived from normal tissues.